Glucose-Raising Polymorphisms in the Human Clock Gene Cryptochrome 2 (CRY2) Affect Hepatic Lipid Content

Circadian rhythms govern vital functions. Their disruption provokes metabolic imbalance favouring obesity and type-2 diabetes. The aim of the study was to assess the role of clock genes in human prediabetes. To this end, genotype-phenotype associations of 121 common single nucleotide polymorphisms (...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Machicao, Fausto, Peter, Andreas, Machann, Jürgen, Königsrainer, Ingmar, Böhm, Anja, Lutz, Stefan Zoltan, Heni, Martin, Fritsche, Andreas, Schick, Fritz, Königsrainer, Alfred, Stefan, Norbert, Häring, Hans-Ulrich, Staiger, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699770/
https://ncbi.nlm.nih.gov/pubmed/26726810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145563
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