Common Genetic Variation in the Human CTF1 Locus, Encoding Cardiotrophin-1, Determines Insulin Sensitivity

AIMS/HYPOTHESIS: Recently, cardiotrophin-1, a member of the interleukin-6 family of cytokines was described to protect beta-cells from apoptosis, to improve glucose-stimulated insulin secretion and insulin resistance, and to prevent streptozotocin-induced diabetes in mice. Here, we studied whether c...

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Main Authors: Lutz, Stefan Z., Franck, Olga, Böhm, Anja, Machann, Jürgen, Schick, Fritz, Machicao, Fausto, Fritsche, Andreas, Häring, Hans-Ulrich, Staiger, Harald
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099130/
https://ncbi.nlm.nih.gov/pubmed/25025664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100391
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