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Design, synthesis, and biological evaluation of novel arylcarboxamide derivatives as anti-tubercular agents

Our group has previously reported several indolecarboxamides exhibiting potent antitubercular activity. Herein, we rationally designed several arylcarboxamides based on our previously reported homology model and the recently published crystal structure of the mycobacterial membrane protein large 3 (...

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Detalhes bibliográficos
Publicado no:RSC Adv
Main Authors: Alsayed, Shahinda S. R., Lun, Shichun, Luna, Giuseppe, Beh, Chau Chun, Payne, Alan D., Foster, Neil, Bishai, William R., Gunosewoyo, Hendra
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497412/
https://ncbi.nlm.nih.gov/pubmed/33014349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ra10663d
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