Reduced expression of the glucocorticoid receptor in the hippocampus of patients with drug‐resistant temporal lobe epilepsy and comorbid depression

OBJECTIVE: Depressive disorders are common among about 50% of the patients with drug‐resistant temporal lobe epilepsy (TLE). The underlying etiology remains elusive, but hypothalamus‐pituitary‐adrenal (HPA) axis activation due to changes in glucocorticoid receptor (GR) protein expression could play...

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Detalhes bibliográficos
Publicado no:Epilepsia
Main Authors: D’Alessio, Luciana, Mesarosova, Lucia, Anink, Jasper J., Kochen, Silvia, Solís, Patricia, Oddo, Silvia, Konopka, Hector, Iyer, Anand M., Mühlebner, Angelika, Lucassen, Paul J., Aronica, Eleonora, van Vliet, Erwin A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Full‐length Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496961/
https://ncbi.nlm.nih.gov/pubmed/32652588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.16598
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