Expression and Cellular Distribution of P-Glycoprotein and Breast Cancer Resistance Protein in Amyotrophic Lateral Sclerosis Patients

For amyotrophic lateral sclerosis (ALS), achieving and maintaining effective drug levels in the brain is challenging due to the activity of ATP-binding cassette (ABC) transporters which efflux drugs that affect drug exposure and response in the brain. We investigated the expression and cellular dist...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: van Vliet, Erwin A, Iyer, Anand M, Mesarosova, Lucia, Çolakoglu, Hilal, Anink, Jasper J, van Tellingen, Olaf, Maragakis, Nicholas J, Shefner, Jeremy, Bunt, Ton, Aronica, Eleonora
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036662/
https://ncbi.nlm.nih.gov/pubmed/31999342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlz142
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