Expression and Cellular Distribution of P-Glycoprotein and Breast Cancer Resistance Protein in Amyotrophic Lateral Sclerosis Patients

For amyotrophic lateral sclerosis (ALS), achieving and maintaining effective drug levels in the brain is challenging due to the activity of ATP-binding cassette (ABC) transporters which efflux drugs that affect drug exposure and response in the brain. We investigated the expression and cellular dist...

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Publicado en:J Neuropathol Exp Neurol
Autores principales: van Vliet, Erwin A, Iyer, Anand M, Mesarosova, Lucia, Çolakoglu, Hilal, Anink, Jasper J, van Tellingen, Olaf, Maragakis, Nicholas J, Shefner, Jeremy, Bunt, Ton, Aronica, Eleonora
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036662/
https://ncbi.nlm.nih.gov/pubmed/31999342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlz142
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