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Developmental patterns of DR6 in normal human hippocampus and in Down syndrome

BACKGROUND: Death receptor 6 (DR6) is highly expressed in the human brain: it has been shown to induce axon pruning and neuron death via distinct caspases and to mediate axonal degeneration through binding to N-terminal β amyloid precursor protein (N-APP). METHODS: We investigated the expression of...

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Autori principali: Iyer, Anand, van Scheppingen, Jackelien, Anink, Jasper, Milenkovic, Ivan, Kovács, Gabor G, Aronica, Eleonora
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666921/
https://ncbi.nlm.nih.gov/pubmed/23618225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1866-1955-5-10
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