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Engineering Orthogonal Methyltransferases to Create Alternative Bioalkylation Pathways
S‐adenosyl‐l‐methionine (SAM)‐dependent methyltransferases (MTs) catalyse the methylation of a vast array of small metabolites and biomacromolecules. Recently, rare carboxymethylation pathways have been discovered, including carboxymethyltransferase enzymes that utilise a carboxy‐SAM (cxSAM) cofacto...
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| Publicat a: | Angew Chem Int Ed Engl |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7496830/ https://ncbi.nlm.nih.gov/pubmed/32402113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202004963 |
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