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Generation of multiepitope cancer vaccines based on large combinatorial libraries of survivin‐derived mutant epitopes
Immune tolerance is the main challenge in the field of cancer vaccines, so modified peptide sequences or naturally occurring mutated versions of cancer‐related wild‐type (WT) antigens represent a promising pathway. However, the low immunogenicity of mutation‐induced neoantigens and, particularly, th...
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| Publicado no: | Immunology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7496785/ https://ncbi.nlm.nih.gov/pubmed/32619293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13233 |
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