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The contribution of Parkin, PINK1 and DJ‐1 genes to selective neuronal degeneration in Parkinson's disease

Parkinson's disease (PD) is characterised by selective and severe degeneration of the substantia nigra pars compacta and the locus coeruleus (LC), which underlies the most prominent symptoms. Although α‐synuclein accumulation has long been established to play a causal role in the disease, it al...

Ausführliche Beschreibung

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Veröffentlicht in:Eur J Neurosci
Hauptverfasser: van der Vlag, Marc, Havekes, Robbert, Heckman, Pim R. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496448/
https://ncbi.nlm.nih.gov/pubmed/31991026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.14689
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