RNA Interference Therapy With ARC‐520 Results in Prolonged Hepatitis B Surface Antigen Response in Patients With Chronic Hepatitis B Infection

BACKGROUND AND AIMS: ARC‐520, the first an RNA interference (RNAi) therapeutic, was designed to reduce all RNA transcripts derived from covalently closed circular DNA, leading to a reduction in viral antigens and hepatitis B virus (HBV) DNA. APPROACH AND RESULTS: We aimed to evaluate the depth of he...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hepatology
Egile Nagusiak: Yuen, Man‐Fung, Schiefke, Ingolf, Yoon, Jung‐Hwan, Ahn, Sang Hoon, Heo, Jeong, Kim, Ju Hyun, Lik Yuen Chan, Henry, Yoon, Ki Tae, Klinker, Hartwig, Manns, Michael, Petersen, Joerg, Schluep, Thomas, Hamilton, James, Given, Bruce D., Ferrari, Carlo, Lai, Ching‐Lung, Locarnini, Stephen A., Gish, Robert G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496196/
https://ncbi.nlm.nih.gov/pubmed/31654573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31008
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