RNA Interference Therapy With ARC‐520 Results in Prolonged Hepatitis B Surface Antigen Response in Patients With Chronic Hepatitis B Infection

BACKGROUND AND AIMS: ARC‐520, the first an RNA interference (RNAi) therapeutic, was designed to reduce all RNA transcripts derived from covalently closed circular DNA, leading to a reduction in viral antigens and hepatitis B virus (HBV) DNA. APPROACH AND RESULTS: We aimed to evaluate the depth of he...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Hepatology
मुख्य लेखकों: Yuen, Man‐Fung, Schiefke, Ingolf, Yoon, Jung‐Hwan, Ahn, Sang Hoon, Heo, Jeong, Kim, Ju Hyun, Lik Yuen Chan, Henry, Yoon, Ki Tae, Klinker, Hartwig, Manns, Michael, Petersen, Joerg, Schluep, Thomas, Hamilton, James, Given, Bruce D., Ferrari, Carlo, Lai, Ching‐Lung, Locarnini, Stephen A., Gish, Robert G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2020
विषय:
Original Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496196/
https://ncbi.nlm.nih.gov/pubmed/31654573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31008
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