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Prey for the Proteasome: Targeted Protein Degradation—A Medicinal Chemist's Perspective

Targeted protein degradation (TPD), the ability to control a proteins fate by triggering its degradation in a highly selective and effective manner, has created tremendous excitement in chemical biology and drug discovery within the past decades. The TPD field is spearheaded by small molecule induce...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Luh, Laura M., Scheib, Ulrike, Juenemann, Katrin, Wortmann, Lars, Brands, Michael, Cromm, Philipp M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496094/
https://ncbi.nlm.nih.gov/pubmed/32428344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202004310
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