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Multiple Reaction Pathways in the Morphinone Reductase-Catalyzed Hydride Transfer Reaction

[Image: see text] Morphinone reductase (MR) is an important model system for studying the contribution of protein motions to H-transfer reactions. In this research, we used quantum mechanical/molecular mechanics (QM/MM) simulation together with transition path sampling (TPS) simulation to study two...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Chen, Xi, Schwartz, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496013/
https://ncbi.nlm.nih.gov/pubmed/32954200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c03472
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