Correction of Airway Stem Cells: Genome Editing Approaches for the Treatment of Cystic Fibrosis

Cystic fibrosis (CF) is an autosomal recessive disease caused by variations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Although CF affects multiple organs, the primary cause of mortality is respiratory failure resulting from poor clearance of hyperviscous secretions and...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: King, Nicholas E., Suzuki, Shingo, Barillà, Cristina, Hawkins, Finn J., Randell, Scott H., Reynolds, Susan D., Stripp, Barry R., Davis, Brian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
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Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495916/
https://ncbi.nlm.nih.gov/pubmed/32741223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2020.160
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