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Challenges Facing Airway Epithelial Cell-Based Therapy for Cystic Fibrosis
Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause the life-limiting hereditary disease, cystic fibrosis (CF). Decreased or absent functional CFTR protein in airway epithelial cells leads to abnormally viscous mucus and impaired mucociliary transport, resulting in...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6376457/ https://ncbi.nlm.nih.gov/pubmed/30800069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00074 |
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