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Challenges Facing Airway Epithelial Cell-Based Therapy for Cystic Fibrosis

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause the life-limiting hereditary disease, cystic fibrosis (CF). Decreased or absent functional CFTR protein in airway epithelial cells leads to abnormally viscous mucus and impaired mucociliary transport, resulting in...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Berical, Andrew, Lee, Rhianna E., Randell, Scott H., Hawkins, Finn
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376457/
https://ncbi.nlm.nih.gov/pubmed/30800069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00074
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