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Computationally identifying hot spots in protein-DNA binding interfaces using an ensemble approach
BACKGROUND: Protein-DNA interaction governs a large number of cellular processes, and it can be altered by a small fraction of interface residues, i.e., the so-called hot spots, which account for most of the interface binding free energy. Accurate prediction of hot spots is critical to understand th...
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| Publicado en: | BMC Bioinformatics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7495898/ https://ncbi.nlm.nih.gov/pubmed/32938375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03675-3 |
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