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Effects of low and high doses of fenofibrate on protein, amino acid, and energy metabolism in rat

A feared adverse effect of dyslipidaemia therapy by fibrates is myopathy. We examined the effect of fenofibrate (FF) on protein and amino acid metabolism. Rats received a low (50 mg/kg, LFFD) or high (300 mg/kg, HFFD) dose of FF or vehicle daily by oral gavage. Blood plasma, liver, and soleus and ex...

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Bibliografiske detaljer
Udgivet i:Int J Exp Pathol
Main Authors: Holeček, Milan, Vodeničarovová, Melita
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495799/
https://ncbi.nlm.nih.gov/pubmed/32869427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12368
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