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Phenylbutyrate exerts adverse effects on liver regeneration and amino acid concentrations in partially hepatectomized rats

Phenylbutyrate is recommended in urea cycle disorders and liver injury to enhance nitrogen disposal by the urine. However, hypothetically there may be adverse responses to the use of phenylbutyrate in the treatment of liver disease because of its role as a histone deacetylase inhibitor and its stimu...

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Detalhes bibliográficos
Publicado no:Int J Exp Pathol
Main Authors: Holecek, Milan, Vodenicarovova, Melita
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960577/
https://ncbi.nlm.nih.gov/pubmed/27381898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12190
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