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Acute effects of phenylbutyrate on glutamine, branched‐chain amino acid and protein metabolism in skeletal muscles of rats

Phenylbutyrate (PB) acts as chemical chaperone and histone deacetylase inhibitor, which is used to decrease ammonia in urea cycle disorders and has been investigated for use in the treatment of a number of lethal illnesses. We performed in vivo and in vitro experiments to examine the effects of PB o...

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Detalhes bibliográficos
Publicado no:Int J Exp Pathol
Main Authors: Holecek, Milan, Vodenicarovova, Melita, Siman, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573773/
https://ncbi.nlm.nih.gov/pubmed/28621016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12231
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