Promiscuous DNA cleavage by HpyAII endonuclease is modulated by the HNH catalytic residues

Helicobacter pylori is a carcinogenic bacterium that is responsible for 5.5% of all human gastric cancers. H. pylori codes for an unusually large number of restriction–modification (R–M) systems and several of them are strain-specific and phase-variable. HpyAII is a novel Type IIs phase-variable res...

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Bibliographische Detailangaben
Veröffentlicht in:Biosci Rep
Hauptverfasser: Kumar, Sumith, Bangru, Sushant, Kumar, Ritesh, Rao, Desirazu N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2020
Schlagworte:
Protein Engineering
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494987/
https://ncbi.nlm.nih.gov/pubmed/32880391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20201633
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