טוען...

A Measure of the Promiscuity of Proteins and Characteristics of Residues in the Vicinity of the Catalytic Site That Regulate Promiscuity

Promiscuity, the basis for the evolution of new functions through ‘tinkering’ of residues in the vicinity of the catalytic site, is yet to be quantitatively defined. We present a computational method Promiscuity Indices Estimator (PROMISE) - based on signatures derived from the spatial and electrost...

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מידע ביבליוגרפי
Main Authors: Chakraborty, Sandeep, Rao, Basuthkar J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281107/
https://ncbi.nlm.nih.gov/pubmed/22359655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032011
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