CDK9 activity is critical for maintaining MDM4 overexpression in tumor cells

The identification of the essential role of cyclin-dependent kinases (CDKs) in the control of cell division has prompted the development of small-molecule CDK inhibitors as anticancer drugs. For many of these compounds, the precise mechanism of action in individual tumor types remains unclear as the...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Štětková, Monika, Growková, Kateřina, Fojtík, Petr, Valčíková, Barbora, Palušová, Veronika, Verlande, Amandine, Jorda, Radek, Kryštof, Vladimír, Hejret, Václav, Alexiou, Panagiotis, Rotrekl, Vladimír, Uldrijan, Stjepan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494941/
https://ncbi.nlm.nih.gov/pubmed/32934219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02971-3
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