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CDK9 activity is critical for maintaining MDM4 overexpression in tumor cells
The identification of the essential role of cyclin-dependent kinases (CDKs) in the control of cell division has prompted the development of small-molecule CDK inhibitors as anticancer drugs. For many of these compounds, the precise mechanism of action in individual tumor types remains unclear as the...
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| Опубликовано в: : | Cell Death Dis |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7494941/ https://ncbi.nlm.nih.gov/pubmed/32934219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02971-3 |
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