Oleanolic Acid Acetate Alleviates Symptoms of Experimental Autoimmune Encephalomyelitis in Mice by Regulating Toll-Like Receptor 2 Signaling

Toll-like receptor 2 (TLR2) is expressed by several immune cells in the central nervous system and plays an important role in neuroinflammation. TLR2 upregulation has been reported in multiple sclerosis patients and in experimental autoimmune encephalomyelitis (EAE), a mouse model for multiple scler...

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Vydáno v:Front Pharmacol
Hlavní autoři: Kim, Minju, Lee, Soyoung, Lim, Hyungjin, Lee, Jihye, Park, Ji-Young, Kwon, Hyung-Jun, Lee, In-Chul, Ryu, Young-Bae, Kim, Jeongtae, Shin, Taekyun, Ahn, Ginnae, Rho, Mun-Chual, Jung, Kyungsook
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494849/
https://ncbi.nlm.nih.gov/pubmed/33013394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.556391
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