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Oleanolic Acid Acetate Exerts Anti-Inflammatory Activity via IKKα/β Suppression in TLR3-Mediated NF-κB Activation

Oleanolic acid acetate (OAA), a major triterpenoid compound of Vigna angularis (azuki bean, V. angularis), has been shown to downregulate inflammatory responses in macrophages. Here, we show the molecular basis for the effect of OAA on Toll-like receptor (TLR) downstream signaling. OAA treatment sig...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Lim, Hyung Jin, Jang, Hyun-Jae, Kim, Mi Hwa, Lee, Soyoung, Lee, Seung Woong, Lee, Seung-Jae, Rho, Mun-Chual
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6866124/
https://ncbi.nlm.nih.gov/pubmed/31694243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24214002
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