Oleanolic Acid Acetate Alleviates Symptoms of Experimental Autoimmune Encephalomyelitis in Mice by Regulating Toll-Like Receptor 2 Signaling

Toll-like receptor 2 (TLR2) is expressed by several immune cells in the central nervous system and plays an important role in neuroinflammation. TLR2 upregulation has been reported in multiple sclerosis patients and in experimental autoimmune encephalomyelitis (EAE), a mouse model for multiple scler...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Kim, Minju, Lee, Soyoung, Lim, Hyungjin, Lee, Jihye, Park, Ji-Young, Kwon, Hyung-Jun, Lee, In-Chul, Ryu, Young-Bae, Kim, Jeongtae, Shin, Taekyun, Ahn, Ginnae, Rho, Mun-Chual, Jung, Kyungsook
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494849/
https://ncbi.nlm.nih.gov/pubmed/33013394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.556391
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