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Mitochondrial Complex I mutations predispose Drosophila to isoflurane neurotoxicity

BACKGROUND: General anesthetics influence mitochondrial homeostasis, placing individuals with mitochondrial disorders and possibly carriers of recessive mitochondrial mutations at increased risk of perioperative complications. In Drosophila, mutations in the ND23 subunit of Complex I of the mitochon...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Anesthesiology
Main Authors: Olufs, Zachariah P. G., Ganetzky, Barry, Wassarman, David A., Perouansky, Misha
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494633/
https://ncbi.nlm.nih.gov/pubmed/32773682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000003486
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