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Isoflurane Selectively Inhibits Distal Mitochondrial Complex I in Caenorhabditis Elegans
BACKGROUND: Complex I of the electron transport chain (ETC) is a possible target of volatile anesthetics (VAs). Complex I enzymatic activities are inhibited by VAs, and dysfunction of complex I can lead to hypersensitivity to VAs in worms and in people. Mutant analysis in Caenorhabditis (C.) elegans...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3102776/ https://ncbi.nlm.nih.gov/pubmed/21467554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e3182121d37 |
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