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Genetic variability affects absolute and relative potencies and kinetics of the anesthetics isoflurane and sevoflurane in Drosophila melanogaster
Genetic variability affects the response to numerous xenobiotics but its role in the clinically-observed irregular responses to general anesthetics remains uncertain. To investigate the pharmacogenetics of volatile general anesthetics (VGAs), we developed a Serial Anesthesia Array apparatus to expos...
Shranjeno v:
izdano v: | Sci Rep |
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Main Authors: | , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Nature Publishing Group UK
2018
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5799260/ https://ncbi.nlm.nih.gov/pubmed/29402974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20720-7 |
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