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Development of chiral fluorinated alkyl derivatives of emixustat as drug candidates for the treatment of retinal degenerative diseases

The discovery of how a photon is converted into a chemical signal is one of the most important achievements in the field of vision. A key molecule in this process is the visual chromophore retinal. Several eye diseases are attributed to the abnormal metabolism of retinal in the retina and the retina...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bioorg Med Chem Lett
Egile Nagusiak: Blum, Eliav, Zhang, Jianye, Korshin, Edward, Palczewski, Krzysztof, Gruzman, Arie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494577/
https://ncbi.nlm.nih.gov/pubmed/32717613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2020.127421
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