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Development of chiral fluorinated alkyl derivatives of emixustat as drug candidates for the treatment of retinal degenerative diseases
The discovery of how a photon is converted into a chemical signal is one of the most important achievements in the field of vision. A key molecule in this process is the visual chromophore retinal. Several eye diseases are attributed to the abnormal metabolism of retinal in the retina and the retina...
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| Pubblicato in: | Bioorg Med Chem Lett |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7494577/ https://ncbi.nlm.nih.gov/pubmed/32717613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2020.127421 |
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