Tuning the Innate Immune Response to Cyclic Dinucleotides Using Atomic Mutagenesis

Cyclic dinucleotides (CDNs) trigger the innate immune response in eukaryotic cells through the STING (stimulator of interferon genes) signalling pathway. To decipher this complex cellular process, a better correlation between structure and downstream function is required. Here we report the design a...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Chembiochem
Auteurs principaux: Li, Yao, Fin, Andrea, Rovira, Alexander R., Su, Yichi, Dippel, Andrew B., Valderrama, Jonathan Andrés, Riestra, Angelica M., Nizet, Victor, Hammond, Ming C., Tor, Yitzhak
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494572/
https://ncbi.nlm.nih.gov/pubmed/32346955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000162
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires