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Telomere Stress Potentiates STING-Dependent Anti-Tumor Immunity
Telomerase is an attractive target for anti-tumor therapy as it is almost universally expressed in cancer cells. Here we show that treatment with a telomere-targeting drug, 6-thio-2’-deoxyguanosine (6-thio-dG), leads to tumor regression through innate and adaptive immune-dependent responses in synge...
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| Udgivet i: | Cancer Cell |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7494563/ https://ncbi.nlm.nih.gov/pubmed/32619407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.05.020 |
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