Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling

The small GTPase RhoA is a central signaling enzyme that is involved in various cellular processes such as cytoskeletal dynamics, transcription, and cell cycle progression. Many signal transduction pathways activate RhoA—for instance, Gα(q)-coupled Histamine 1 Receptor signaling via Gα(q)-dependent...

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Bibliografiske detaljer
Udgivet i:PLoS Biol
Main Authors: Zhang, Jason Z., Nguyen, Andy H., Miyamoto, Shigeki, Heller Brown, Joan, McCulloch, Andrew D., Zhang, Jin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Short Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494096/
https://ncbi.nlm.nih.gov/pubmed/32881857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000866
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