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Myocardin-Related Transcription Factor A and Yes-Associated Protein Exert Dual Control in G Protein-Coupled Receptor- and RhoA-Mediated Transcriptional Regulation and Cell Proliferation

The ability of a subset of G protein-coupled receptors (GPCRs) to activate RhoA endows them with unique growth-regulatory properties. Two transcriptional pathways are activated through GPCRs and RhoA, one utilizing the transcriptional coactivator myocardin-related transcription factor A (MRTF-A) and...

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Pubblicato in:Mol Cell Biol
Autori principali: Yu, Olivia M., Miyamoto, Shigeki, Brown, Joan Heller
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702594/
https://ncbi.nlm.nih.gov/pubmed/26459764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00772-15
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