NS5-V372A and NS5-H386Y variations are responsible for differences in interferon α/β induction and co-contribute to the replication advantage of Japanese encephalitis virus genotype I over genotype III in ducklings

Japanese encephalitis virus (JEV) genotype I (GI) replicates more efficiently than genotype III (GIII) in birds, and this difference is considered to be one of the reasons for the JEV genotype shift. In this study, we utilized duck embryo fibroblasts and domestic ducklings as in vitro and in vivo mo...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS Pathog
Main Authors: Li, Chenxi, Di, Di, Huang, Hui, Wang, Xin, Xia, Qiqi, Ma, Xiaochun, Liu, Ke, Li, Beibei, Shao, Donghua, Qiu, Yafeng, Li, Zongjie, Wei, Jianchao, Ma, Zhiyong
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2020
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494076/
https://ncbi.nlm.nih.gov/pubmed/32881988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008773
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