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A newly discovered role of metabolic enzyme PCK1 as a protein kinase to promote cancer lipogenesis

Highly active lipogenesis is essential for rapid tumor growth. Sterol regulatory element‐binding protein (SREBP) is a key transcriptional factor for lipogenesis and activated by reduced sterol and oxysterol levels. However, the mechanism by which cancer cells activate SREBP without altering these st...

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Bibliografski detalji
Izdano u:Cancer Commun (Lond)
Glavni autori: Jiang, Hongfei, Zhu, Lei, Xu, Daqian, Lu, Zhimin
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494067/
https://ncbi.nlm.nih.gov/pubmed/32809272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cac2.12084
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