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A newly discovered role of metabolic enzyme PCK1 as a protein kinase to promote cancer lipogenesis
Highly active lipogenesis is essential for rapid tumor growth. Sterol regulatory element‐binding protein (SREBP) is a key transcriptional factor for lipogenesis and activated by reduced sterol and oxysterol levels. However, the mechanism by which cancer cells activate SREBP without altering these st...
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| Publicado no: | Cancer Commun (Lond) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7494067/ https://ncbi.nlm.nih.gov/pubmed/32809272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cac2.12084 |
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