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Recognition of Human IgG1 by Fcγ Receptors: Structural Insights from Hydrogen-Deuterium Exchange and Fast Photochemical Oxidation of Proteins Coupled with Mass Spectrometry

Antibody-dependent cell-mediated cytotoxicity (ADCC) is an effector function of immunoglobulins (IgGs) involved in the killing of target cells by a cytotoxic effector cell. Recognition of IgG by Fc receptors expressed on natural killer cells, mostly FcγIII receptors (FcγRIII), underpins the ADCC mec...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Shi, Liuqing, Liu, Tun, Gross, Michael L., Huang, Yining
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493818/
https://ncbi.nlm.nih.gov/pubmed/30666863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01048
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