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Failure of target attainment of beta-lactam antibiotics in critically ill patients and associated risk factors: a two-center prospective study (EXPAT)

BACKGROUND: Early and appropriate antibiotic dosing is associated with improved clinical outcomes in critically ill patients, yet target attainment remains a challenge. Traditional antibiotic dosing is not suitable in critically ill patients, since these patients undergo physiological alterations th...

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Publicado en:Crit Care
Main Authors: Abdulla, Alan, Dijkstra, Annemieke, Hunfeld, Nicole G. M., Endeman, Henrik, Bahmany, Soma, Ewoldt, Tim M. J., Muller, Anouk E., van Gelder, Teun, Gommers, Diederik, Koch, Birgit C. P.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493358/
https://ncbi.nlm.nih.gov/pubmed/32933574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-020-03272-z
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