Population pharmacokinetics and target attainment of ciprofloxacin in critically ill patients

PURPOSE: To develop and validate a population pharmacokinetic model of ciprofloxacin intravenously in critically ill patients, and determine target attainment to provide guidance for more effective regimens. METHODS: Non-linear mixed-effects modelling was used for the model development and covariate...

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Publicat a:Eur J Clin Pharmacol
Autors principals: Abdulla, Alan, Rogouti, Omar, Hunfeld, Nicole G. M., Endeman, Henrik, Dijkstra, Annemieke, van Gelder, Teun, Muller, Anouk E., de Winter, Brenda C. M., Koch, Birgit C. P.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2020
Matèries:
Pharmacokinetics and Disposition
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306030/
https://ncbi.nlm.nih.gov/pubmed/32307575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-020-02873-5
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