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Cofactor Generation Cascade for α-Ketoglutarate and Fe(II)-Dependent Dioxygenases

[Image: see text] Fe(II)- and α-ketoglutarate dependent dioxygenases have emerged as important catalysts for the preparation of non-natural amino acids. The stoichiometric supply of the cosubstrate α-ketoglutarate (αKG) is an important cost factor. A combination of the N-succinyl amino acid hydroxyl...

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Publicat a:ACS Sustain Chem Eng
Autors principals: Busch, Florian, Brummund, Jan, Calderini, Elia, Schürmann, Martin, Kourist, Robert
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493210/
https://ncbi.nlm.nih.gov/pubmed/32953283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssuschemeng.0c01122
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