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Offloading Role of a Discrete Thioesterase in Type II Polyketide Biosynthesis

Type II polyketides are a group of secondary metabolites with various biological activities. In nature, biosynthesis of type II polyketides involves multiple enzymatic steps whereby key enzymes, including ketoacyl-synthase (KS(α)), chain length factor (KS(β)), and acyl carrier protein (ACP), are uti...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Hua, Kangmin, Liu, Xiangyang, Zhao, Yuchun, Gao, Yaojie, Pan, Lifeng, Zhang, Haoran, Deng, Zixin, Jiang, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492732/
https://ncbi.nlm.nih.gov/pubmed/32934080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01334-20
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