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Role of Ubiquitination in PTEN Cellular Homeostasis and Its Implications in GB Drug Resistance
Glioblastoma (GB) is the most common and aggressive brain malignancy, characterized by heterogeneity and drug resistance. PTEN, a crucial tumor suppressor, exhibits phosphatase-dependent (PI3K-AKT-mTOR pathway)/independent (nucleus stability) activities to maintain the homeostatic regulation of nume...
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| Publicado no: | Front Oncol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7492558/ https://ncbi.nlm.nih.gov/pubmed/32984016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01569 |
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