Therapeutic Potential of Autophagy in Glioblastoma Treatment With Phosphoinositide 3-Kinase/Protein Kinase B/Mammalian Target of Rapamycin Signaling Pathway Inhibitors

Glioblastoma (GB) is the most malignant and aggressive form of brain tumor, characterized by frequent hyperactivation of the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway. PI3K/AKT/mTOR inhibitors have a promising clinical efficacy the...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Xia, Qin, Xu, Mengchuan, Zhang, Pei, Liu, Liqun, Meng, Xinyi, Dong, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567033/
https://ncbi.nlm.nih.gov/pubmed/33123479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.572904
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