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Quantile-specific heritability of high-density lipoproteins with implications for precision medicine

BACKGROUND: We have previously shown that the effect of an HDL genetic risk score depends upon whether the phenotype (HDL-cholesterol) is high or low relative to its distribution (quantile-dependent expressivity). OBJECTIVE: Evidence for quantile-dependent expressivity was sought using a more inclus...

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Dades bibliogràfiques
Publicat a:J Clin Lipidol
Autor principal: Williams, Paul T
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492391/
https://ncbi.nlm.nih.gov/pubmed/32600822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacl.2020.05.099
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