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Partial and Full Deletion of Nicotinic Acetylcholine Receptor α4 and β2 Subunits Reduces Sensitivity to Acute Nicotine Administration and Development of Tolerance following Chronic Nicotine Administration

The diversity of nicotinic cholinergic receptor (nAChR) subunits underlies the complex responses to nicotine. Mice differing in expression of α4 and β2 subunits, which are most widely expressed in brain, were evaluated for the responses to acute nicotine administration on Y-Maze Crossings and Rears,...

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Publicat a:Behav Pharmacol
Autors principals: Marks, Michael J., Loetz, Esteban, Ortiz, Nick C., Herder, Penelope A., Collins, Allan C.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492369/
https://ncbi.nlm.nih.gov/pubmed/32568759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0000000000000575
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