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Differential expression of the beta4 neuronal nicotinic receptor subunit affects tolerance development and nicotinic binding sites following chronic nicotine treatment

The role of neuronal nicotinic acetylcholine receptors (nAChR) containing the β4 subunit in tolerance development and nicotinic binding site levels following chronic nicotine treatment was investigated. Mice differing in expression of the β4 nAChR subunit [wild-type (β4(++)), heterozygote (β4(+−)) a...

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Publicado en:Pharmacol Biochem Behav
Autores principales: Meyers, Erin E., Loetz, Esteban C., Marks, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336781/
https://ncbi.nlm.nih.gov/pubmed/25560939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2014.12.013
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